IMA-package |
IMA(Illumina Methylation Analyzer) is a package designed to automate the pipeline for exploratory analysis and summarization of site-level and region-level methylation changes in epigenetic studies utilizing the 450K DNA methylation microarray |
annotfunc |
Annotate siteIDs/regionIDs of interest |
exprmethy450 |
Load methylation 450k data |
IMA |
IMA(Illumina Methylation Analyzer) is a package designed to automate the pipeline for exploratory analysis and summarization of site-level and region-level methylation changes in epigenetic studies utilizing the 450K DNA methylation microarray |
IMA.methy450PP |
Data preprocessing and quality control |
IMA.methy450R |
Load methylation 450k data |
indexregionfunc |
Region-level Methylation Index Calculation |
methy450batch |
Data preprocessing and quality control |
outputDMfunc |
Output the differentially methylated sites/regions |
regionswrapper |
Differential methylation testing on all 11 categories of annotated region |
sitetest |
Site-level Differential Methylation Analysis |
testfunc |
Differential methylation testing function |